Cargando…
Epigenetic regulation by RARα maintains ligand-independent transcriptional activity
Retinoic acid receptors (RARs) α, β and γ are key regulators of embryonic development. Hematopoietic differentiation is regulated by RARα, and several types of leukemia show aberrant RARα activity. Through microarray expression analysis, we identified transcripts differentially expressed between F9...
Autores principales: | Laursen, Kristian B., Wong, Pui-Mun, Gudas, Lorraine J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245912/ https://www.ncbi.nlm.nih.gov/pubmed/21911359 http://dx.doi.org/10.1093/nar/gkr637 |
Ejemplares similares
-
Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene
por: Laursen, Kristian B., et al.
Publicado: (2013) -
Human ADA3 regulates RARα transcriptional activity through direct contact between LxxLL motifs and the receptor coactivator pocket
por: Li, Chia-Wei, et al.
Publicado: (2010) -
A transcription-independent epigenetic mechanism is associated with antigenic switching in Trypanosoma brucei
por: Aresta-Branco, Francisco, et al.
Publicado: (2016) -
RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements
por: Chatagnon, Amandine, et al.
Publicado: (2015) -
FANCJ coordinates two pathways that maintain epigenetic stability at G-quadruplex DNA
por: Sarkies, Peter, et al.
Publicado: (2012)