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Genome-wide H4 K16 acetylation by SAS-I is deposited independently of transcription and histone exchange

The MYST HAT Sas2 is part of the SAS-I complex that acetylates histone H4 lysine 16 (H4 K16Ac) and blocks the propagation of heterochromatin at the telomeres of Saccharomyces cerevisiae. In this study, we investigated Sas2-mediated H4 K16Ac on a genome-wide scale. Interestingly, H4 K16Ac loss in sas...

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Detalles Bibliográficos
Autores principales:	Heise, Franziska, Chung, Ho-Ryun, Weber, Jan M., Xu, Zhenyu, Klein-Hitpass, Ludger, Steinmetz, Lars M., Vingron, Martin, Ehrenhofer-Murray, Ann E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245914/ https://www.ncbi.nlm.nih.gov/pubmed/21908408 http://dx.doi.org/10.1093/nar/gkr649

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