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dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells
Double-stranded RNA (dsRNA) can enter different pathways in mammalian cells, including sequence-specific RNA interference (RNAi), sequence-independent interferon (IFN) response and editing by adenosine deaminases. To study the routing of dsRNA to these pathways in vivo, we used transgenic mice ubiqu...
Autores principales: | Nejepinska, Jana, Malik, Radek, Filkowski, Jody, Flemr, Matyas, Filipowicz, Witold, Svoboda, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245926/ https://www.ncbi.nlm.nih.gov/pubmed/21908396 http://dx.doi.org/10.1093/nar/gkr702 |
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