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Targeted detection of in vivo endogenous DNA base damage reveals preferential base excision repair in the transcribed strand

Endogenous DNA damage is removed mainly via base excision repair (BER), however, whether there is preferential strand repair of endogenous DNA damage is still under intense debate. We developed a highly sensitive primer-anchored DNA damage detection assay (PADDA) to map and quantify in vivo endogeno...

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Detalles Bibliográficos
Autores principales:	Reis, António M. C., Mills, Wilbur K., Ramachandran, Ilangovan, Friedberg, Errol C., Thompson, David, Queimado, Lurdes
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245927/ https://www.ncbi.nlm.nih.gov/pubmed/21911361 http://dx.doi.org/10.1093/nar/gkr704

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