Structure of the Trichomonas vaginalis Myb3 DNA-binding domain bound to a promoter sequence reveals a unique C-terminal β-hairpin conformation

Trichomonas vaginalis Myb3 transcription factor (tvMyb3) recognizes the MRE-1 promoter sequence and regulates ap65-1 gene, which encodes a hydrogenosomal malic enzyme that may play a role in the cytoadherence of the parasite. Here, we identified tvMyb3(53–180) as the essential fragment for DNA recog...

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Detalles Bibliográficos
Autores principales: Wei, Shu-Yi, Lou, Yuan-Chao, Tsai, Jia-Yin, Ho, Meng-Ru, Chou, Chun-Chi, Rajasekaran, M., Hsu, Hong-Ming, Tai, Jung-Hsiang, Hsiao, Chwan-Deng, Chen, Chinpan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245928/
https://www.ncbi.nlm.nih.gov/pubmed/21908401
http://dx.doi.org/10.1093/nar/gkr707

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