Integrated genome-wide analysis of transcription factor occupancy, RNA polymerase II binding and steady-state RNA levels identify differentially regulated functional gene classes

Routine methods for assaying steady-state mRNA levels such as RNA-seq and micro-arrays are commonly used as readouts to study the role of transcription factors (TFs) in gene expression regulation. However, cellular RNA levels do not solely depend on activity of TFs and subsequent transcription by RN...

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Detalles Bibliográficos
Autores principales: Mokry, Michal, Hatzis, Pantelis, Schuijers, Jurian, Lansu, Nico, Ruzius, Frans-Paul, Clevers, Hans, Cuppen, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245935/
https://www.ncbi.nlm.nih.gov/pubmed/21914722
http://dx.doi.org/10.1093/nar/gkr720

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