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Histone hypoacetylation is required to maintain late replication timing of constitutive heterochromatin

The replication of the genome is a spatio-temporally highly organized process. Yet, its flexibility throughout development suggests that this process is not genetically regulated. However, the mechanisms and chromatin modifications controlling replication timing are still unclear. We made use of the...

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Detalles Bibliográficos
Autores principales:	Casas-Delucchi, Corella S., van Bemmel, Joke G., Haase, Sebastian, Herce, Henry D., Nowak, Danny, Meilinger, Daniela, Stear, Jeffrey H., Leonhardt, Heinrich, Cardoso, M. Cristina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245938/ https://www.ncbi.nlm.nih.gov/pubmed/21908399 http://dx.doi.org/10.1093/nar/gkr723

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