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The genome maintenance factor Mgs1 is targeted to sites of replication stress by ubiquitylated PCNA

Mgs1, the budding yeast homolog of mammalian Werner helicase-interacting protein 1 (WRNIP1/WHIP), contributes to genome stability during undisturbed replication and in response to DNA damage. A ubiquitin-binding zinc finger (UBZ) domain directs human WRNIP1 to nuclear foci, but the functional signif...

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Detalles Bibliográficos
Autores principales:	Saugar, Irene, Parker, Joanne L., Zhao, Shengkai, Ulrich, Helle D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245944/ https://www.ncbi.nlm.nih.gov/pubmed/21911365 http://dx.doi.org/10.1093/nar/gkr738

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