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Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform

Due to the increasing throughput of current DNA sequencing instruments, sample multiplexing is necessary for making economical use of available sequencing capacities. A widely used multiplexing strategy for the Illumina Genome Analyzer utilizes sample-specific indexes, which are embedded in one of t...

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Detalles Bibliográficos
Autores principales: Kircher, Martin, Sawyer, Susanna, Meyer, Matthias
Formato: Online Artigo Texto
Idioma:English
Publicado: Oxford University Press 2012
Materias:
Acceso en liña:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245947/
https://www.ncbi.nlm.nih.gov/pubmed/22021376
http://dx.doi.org/10.1093/nar/gkr771