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Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform

Due to the increasing throughput of current DNA sequencing instruments, sample multiplexing is necessary for making economical use of available sequencing capacities. A widely used multiplexing strategy for the Illumina Genome Analyzer utilizes sample-specific indexes, which are embedded in one of t...

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Detalhes bibliográficos
Principais autores: Kircher, Martin, Sawyer, Susanna, Meyer, Matthias
Formato: Online Atigo Texto
Idioma:English
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245947/
https://www.ncbi.nlm.nih.gov/pubmed/22021376
http://dx.doi.org/10.1093/nar/gkr771