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Mutation Rate Inferred From Synonymous Substitutions in a Long-Term Evolution Experiment With Escherichia coli

The quantification of spontaneous mutation rates is crucial for a mechanistic understanding of the evolutionary process. In bacteria, traditional estimates using experimental or comparative genetic methods are prone to statistical uncertainty and consequently estimates vary by over one order of magn...

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Detalles Bibliográficos
Autores principales:	Wielgoss, Sébastien, Barrick, Jeffrey E., Tenaillon, Olivier, Cruveiller, Stéphane, Chane-Woon-Ming, Béatrice, Médigue, Claudine, Lenski, Richard E., Schneider, Dominique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2011
Materias:	Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246271/ https://www.ncbi.nlm.nih.gov/pubmed/22207905 http://dx.doi.org/10.1534/g3.111.000406

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