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Functional Induction of the Cystine-Glutamate Exchanger System X(c) (-) Activity in SH-SY5Y Cells by Unconjugated Bilirubin

We have previously reported that exposure of SH-SY5Y neuroblastoma cells to unconjugated bilirubin (UCB) resulted in a marked up-regulation of the mRNA encoding for the Na(+) -independent cystine∶glutamate exchanger System X(c) (−) (SLC7A11 and SLC3A2 genes). In this study we demonstrate that SH-SY5...

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Detalles Bibliográficos
Autores principales:	Giraudi, Pablo J., Bellarosa, Cristina, Coda-Zabetta, Carlos D., Peruzzo, Paolo, Tiribelli, Claudio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246462/ https://www.ncbi.nlm.nih.gov/pubmed/22216172 http://dx.doi.org/10.1371/journal.pone.0029078

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