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General Anesthetics Inhibit Erythropoietin Induction under Hypoxic Conditions in the Mouse Brain

BACKGROUND: Erythropoietin (EPO), originally identified as a hematopoietic growth factor produced in the kidney and fetal liver, is also endogenously expressed in the central nervous system (CNS). EPO in the CNS, mainly produced in astrocytes, is induced under hypoxic conditions in a hypoxia-inducib...

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Detalles Bibliográficos
Autores principales: Tanaka, Tomoharu, Kai, Shinichi, Koyama, Tomohiro, Daijo, Hiroki, Adachi, Takehiko, Fukuda, Kazuhiko, Hirota, Kiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246473/
https://www.ncbi.nlm.nih.gov/pubmed/22216265
http://dx.doi.org/10.1371/journal.pone.0029378