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Extremely High Tp53 Mutation Load in Esophageal Squamous Cell Carcinoma in Golestan Province, Iran
BACKGROUND: Golestan Province in northeastern Iran has one of the highest incidences of esophageal squamous cell carcinoma (ESCC) in the world with rates over 50 per 100,000 person-years in both sexes. We have analyzed TP53 mutation patterns in tumors from this high-risk geographic area in search of...
Autores principales: | Abedi-Ardekani, Behnoush, Kamangar, Farin, Sotoudeh, Masoud, Villar, Stephanie, Islami, Farhad, Aghcheli, Karim, Nasrollahzadeh, Dariush, Taghavi, Noushin, Dawsey, Sanford M., Abnet, Christian C., Hewitt, Stephen M., Fahimi, Saman, Saidi, Farrokh, Brennan, Paul, Boffetta, Paolo, Malekzadeh, Reza, Hainaut, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246475/ https://www.ncbi.nlm.nih.gov/pubmed/22216294 http://dx.doi.org/10.1371/journal.pone.0029488 |
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