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Duffy Antigen Receptor for Chemokines Mediates Chemokine Endocytosis through a Macropinocytosis-Like Process in Endothelial Cells

BACKGROUND: The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes and endothelial cells. Recent evidence suggests that endothelial DARC facilitates chemokine transcytosis to promote neutrophil recr...

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Detalles Bibliográficos
Autores principales: Zhao, Yani, Mangalmurti, Nilam S., Xiong, Zeyu, Prakash, Bharat, Guo, Fengli, Stolz, Donna B., Lee, Janet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246497/
https://www.ncbi.nlm.nih.gov/pubmed/22216333
http://dx.doi.org/10.1371/journal.pone.0029624