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Duffy Antigen Receptor for Chemokines Mediates Chemokine Endocytosis through a Macropinocytosis-Like Process in Endothelial Cells
BACKGROUND: The Duffy antigen receptor for chemokines (DARC) shows high affinity binding to multiple inflammatory CC and CXC chemokines and is expressed by erythrocytes and endothelial cells. Recent evidence suggests that endothelial DARC facilitates chemokine transcytosis to promote neutrophil recr...
Autores principales: | Zhao, Yani, Mangalmurti, Nilam S., Xiong, Zeyu, Prakash, Bharat, Guo, Fengli, Stolz, Donna B., Lee, Janet S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246497/ https://www.ncbi.nlm.nih.gov/pubmed/22216333 http://dx.doi.org/10.1371/journal.pone.0029624 |
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