Thymidine Kinase 2 Deficiency-Induced Mitochondrial DNA Depletion Causes Abnormal Development of Adipose Tissues and Adipokine Levels in Mice

Mammal adipose tissues require mitochondrial activity for proper development and differentiation. The components of the mitochondrial respiratory chain/oxidative phosphorylation system (OXPHOS) are encoded by both mitochondrial and nuclear genomes. The maintenance of mitochondrial DNA (mtDNA) is a k...

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Detalles Bibliográficos
Autores principales: Villarroya, Joan, Dorado, Beatriz, Vilà, Maya R., Garcia-Arumí, Elena, Domingo, Pere, Giralt, Marta, Hirano, Michio, Villarroya, Francesc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246498/
https://www.ncbi.nlm.nih.gov/pubmed/22216345
http://dx.doi.org/10.1371/journal.pone.0029691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246498/
https://www.ncbi.nlm.nih.gov/pubmed/22216345
http://dx.doi.org/10.1371/journal.pone.0029691

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