A Comparative Evaluation of Mono-, Di- and Triglyceride of Medium Chain Fatty Acids by Lipid/Surfactant/Water Phase Diagram, Solubility Determination and Dispersion Testing for Application in Pharmaceutical Dosage Form Development

PURPOSE: To compare physiochemical properties of mono-, di- and triglycerides of medium chain fatty acids for development of oral pharmaceutical dosage forms of poorly water-soluble drugs using phase diagrams, drug solubility, and drug dispersion experiments. METHODS: Phase diagrams were prepared us...

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Detalles Bibliográficos
Autores principales: Prajapati, Hetal N., Dalrymple, Damon M., Serajuddin, Abu T. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246583/
https://www.ncbi.nlm.nih.gov/pubmed/21861203
http://dx.doi.org/10.1007/s11095-011-0541-3

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