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Eosinophilic Esophagitis for the Otolaryngologist

Objectives. This paper focuses on current diagnostic and treatment options for Eosinophilic Esophagitis (EE). Study Design. literature review. Results. EE can be suspected on history and endoscopy although definitive diagnosis is strictly based on histopathology. It is a relatively new entity and is...

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Autores principales: Karkos, Petros D., Srivastava, R., Kaptanis, S., Vaughan, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246723/
https://www.ncbi.nlm.nih.gov/pubmed/22220173
http://dx.doi.org/10.1155/2012/181402
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author Karkos, Petros D.
Srivastava, R.
Kaptanis, S.
Vaughan, C.
author_facet Karkos, Petros D.
Srivastava, R.
Kaptanis, S.
Vaughan, C.
author_sort Karkos, Petros D.
collection PubMed
description Objectives. This paper focuses on current diagnostic and treatment options for Eosinophilic Esophagitis (EE). Study Design. literature review. Results. EE can be suspected on history and endoscopy although definitive diagnosis is strictly based on histopathology. It is a relatively new entity and is often misdiagnosed as gastroesophageal reflux (GERD). Eosinophilic infiltration of the esophageal mucosa is responsible for esophageal symptoms which can range from mild to debilitating dysphagia and food impaction, when untreated. In fact recurrent foreign body and food impaction can often be blamed for undiagnosed EE. There seems to be a strong familial component and association with allergy. The introduction of transnasal esophagoscopy in adult laryngology has enabled otolaryngologists to readily diagnose EE and promoted awareness of this often difficult to recognize entity. Conclusions. Despite higher awareness, the literature suggests that EE remains a commonly misdiagnosed condition especially in the otolaryngology community. Genetic studies are required to unfold the true familial and genetic component of this fascinating entity.
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spelling pubmed-32467232012-01-04 Eosinophilic Esophagitis for the Otolaryngologist Karkos, Petros D. Srivastava, R. Kaptanis, S. Vaughan, C. Int J Otolaryngol Review Article Objectives. This paper focuses on current diagnostic and treatment options for Eosinophilic Esophagitis (EE). Study Design. literature review. Results. EE can be suspected on history and endoscopy although definitive diagnosis is strictly based on histopathology. It is a relatively new entity and is often misdiagnosed as gastroesophageal reflux (GERD). Eosinophilic infiltration of the esophageal mucosa is responsible for esophageal symptoms which can range from mild to debilitating dysphagia and food impaction, when untreated. In fact recurrent foreign body and food impaction can often be blamed for undiagnosed EE. There seems to be a strong familial component and association with allergy. The introduction of transnasal esophagoscopy in adult laryngology has enabled otolaryngologists to readily diagnose EE and promoted awareness of this often difficult to recognize entity. Conclusions. Despite higher awareness, the literature suggests that EE remains a commonly misdiagnosed condition especially in the otolaryngology community. Genetic studies are required to unfold the true familial and genetic component of this fascinating entity. Hindawi Publishing Corporation 2012 2011-12-15 /pmc/articles/PMC3246723/ /pubmed/22220173 http://dx.doi.org/10.1155/2012/181402 Text en Copyright © 2012 Petros D. Karkos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Karkos, Petros D.
Srivastava, R.
Kaptanis, S.
Vaughan, C.
Eosinophilic Esophagitis for the Otolaryngologist
title Eosinophilic Esophagitis for the Otolaryngologist
title_full Eosinophilic Esophagitis for the Otolaryngologist
title_fullStr Eosinophilic Esophagitis for the Otolaryngologist
title_full_unstemmed Eosinophilic Esophagitis for the Otolaryngologist
title_short Eosinophilic Esophagitis for the Otolaryngologist
title_sort eosinophilic esophagitis for the otolaryngologist
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246723/
https://www.ncbi.nlm.nih.gov/pubmed/22220173
http://dx.doi.org/10.1155/2012/181402
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AT vaughanc eosinophilicesophagitisfortheotolaryngologist