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The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease
Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246792/ https://www.ncbi.nlm.nih.gov/pubmed/22220178 http://dx.doi.org/10.1155/2012/282348 |
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author | MacLean, S. Khan, W. S. Malik, A. A. Anand, S. Snow, M. |
author_facet | MacLean, S. Khan, W. S. Malik, A. A. Anand, S. Snow, M. |
author_sort | MacLean, S. |
collection | PubMed |
description | Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective benefit to patients with muscle disease/damage. This could include damage to muscle from trauma and include genetic abnormalities, for example, muscular dystrophies. Much of this research thus far has been focused on satellite cells, however, mesenchymal stem cells have more recently come to the fore. In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use. |
format | Online Article Text |
id | pubmed-3246792 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32467922012-01-04 The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease MacLean, S. Khan, W. S. Malik, A. A. Anand, S. Snow, M. Stem Cells Int Review Article Tissue engineering is a pioneering field with huge advances in recent times. These advances are not only in the understanding of how cells can be manipulated but also in potential clinical applications. Thus, tissue engineering, when applied to skeletal muscle cells, is an area of huge prospective benefit to patients with muscle disease/damage. This could include damage to muscle from trauma and include genetic abnormalities, for example, muscular dystrophies. Much of this research thus far has been focused on satellite cells, however, mesenchymal stem cells have more recently come to the fore. In particular, results of trials and further research into their use in heart failure, stress incontinence, and muscular dystrophies are eagerly awaited. Although no doubt, stem cells will have much to offer in the future, the results of further research still limit their use. Hindawi Publishing Corporation 2012 2011-12-19 /pmc/articles/PMC3246792/ /pubmed/22220178 http://dx.doi.org/10.1155/2012/282348 Text en Copyright © 2012 S. MacLean et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article MacLean, S. Khan, W. S. Malik, A. A. Anand, S. Snow, M. The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
title | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
title_full | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
title_fullStr | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
title_full_unstemmed | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
title_short | The Potential of Stem Cells in the Treatment of Skeletal Muscle Injury and Disease |
title_sort | potential of stem cells in the treatment of skeletal muscle injury and disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246792/ https://www.ncbi.nlm.nih.gov/pubmed/22220178 http://dx.doi.org/10.1155/2012/282348 |
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