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Reconstituted synaptotagmin I mediates vesicle docking, priming, and fusion
The synaptic vesicle protein synaptotagmin I (syt) promotes exocytosis via its ability to penetrate membranes in response to binding Ca(2+) and through direct interactions with SNARE proteins. However, studies using full-length (FL) membrane-embedded syt in reconstituted fusion assays have yielded c...
Autores principales: | Wang, Zhao, Liu, Huisheng, Gu, Yiwen, Chapman, Edwin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3246889/ https://www.ncbi.nlm.nih.gov/pubmed/22184197 http://dx.doi.org/10.1083/jcb.201104079 |
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