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Differential regional expression patterns of α-synuclein, TNF-α, and IL-1β; and variable status of dopaminergic neurotoxicity in mouse brain after Paraquat treatment

BACKGROUND: Paraquat (1, 1-dimethyl-4, 4-bipyridium dichloride; PQ) causes neurotoxicity, especially dopaminergic neurotoxicity, and is a supposed risk factor for Parkinson's disease (PD). However, the cellular and molecular mechanisms of PQ-induced neurodegeneration are far from clear. Previou...

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Detalles Bibliográficos
Autores principales:	Mitra, Soham, Chakrabarti, Nilkanta, Bhattacharyya, Arindam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247140/ https://www.ncbi.nlm.nih.gov/pubmed/22112368 http://dx.doi.org/10.1186/1742-2094-8-163

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