Cargando…

Evaluation of cytotoxicity of bevacizumab on VEGF-enriched corneal endothelial cells

PURPOSE: To evaluate the cytotoxicity of varying doses of Bevacizumab on corneal endothelial cells in the presence of a range of concentrations of vascular endothelial growth factor (VEGF). Bevacizumab, a drug widely used in the treatment of neovascular glaucoma neutralizes all isoforms of VEGF and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rusovici, Raluca, Sakhalkar, Monali, Chalam, Kakarla V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Vision 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247162/ https://www.ncbi.nlm.nih.gov/pubmed/22219629

Ejemplares similares

Bevacizumab inhibits proliferation of choroidal endothelial cells by regulation of the cell cycle
por: Rusovici, Raluca, et al.
Publicado: (2013)

The Role of Lutein in Eye-Related Disease
por: Koushan, Keyvan, et al.
Publicado: (2013)

Ocular manifestations of Noonan syndrome in twin siblings: A case report of keratoconus with acute corneal hydrops
por: Lee, Anna, et al.
Publicado: (2014)

Bevacizumab therapy normalizes the pathological intraocular environment beyond neutralizing VEGF
por: Sharma, Rajesh K., et al.
Publicado: (2010)

Aqueous Interleukin-6 Levels Are Superior to Vascular Endothelial Growth Factor in Predicting Therapeutic Response to Bevacizumab in Age-Related Macular Degeneration
por: Chalam, Kakarla V., et al.
Publicado: (2014)

Treatment of Corneal Neovascularization Using Anti-VEGF Bevacizumab
por: Krizova, Deli, et al.
Publicado: (2014)

Hypoxia initiates sirtuin1-mediated vascular endothelial growth factor activation in choroidal endothelial cells through hypoxia inducible factor–2α
por: Balaiya, Sankarathi, et al.
Publicado: (2012)

Resveratrol inhibits proliferation of hypoxic choroidal vascular endothelial cells
por: Balaiya, Sankarathi, et al.
Publicado: (2013)

Pazopanib Selectively Inhibits Choroidal Vascular Endothelial Cell Proliferation and Promotes Apoptosis
por: Mynampati, Bharani, et al.
Publicado: (2020)

Bevacizumab neutralizes the protective effect of vascular endothelial growth factor on retinal ganglion cells
por: Brar, Vikram S., et al.
Publicado: (2010)

Spectral domain optical coherence tomography features of multiple subfoveal retinal pigment epithelial tears after intravitreal bevacizumab
por: Chalam, Kakarla V, et al.
Publicado: (2011)

Effects of ranibizumab (Lucentis®) and bevacizumab (Avastin®) on human corneal endothelial cells
por: Merz, Patrick R., et al.
Publicado: (2018)

Evaluation of moxifloxacin-induced cytotoxicity on human corneal endothelial cells
por: Park, Joo-Hee, et al.
Publicado: (2021)

Freezing adversely affects measurement of vascular endothelial growth factor levels in human aqueous samples
por: Balaiya, Sankarathi, et al.
Publicado: (2011)

Binding and neutralization of vascular endothelial growth factor (VEGF) and related ligands by VEGF Trap, ranibizumab and bevacizumab
por: Papadopoulos, Nicholas, et al.
Publicado: (2012)

Comparison of central corneal thickness: ultrasound pachymetry versus slit-lamp optical coherence tomography, specular microscopy, and Orbscan
por: Khaja, Wassia A, et al.
Publicado: (2015)

Evaluation of ultraviolet light toxicity on cultured retinal pigment epithelial and retinal ganglion cells
por: Balaiya, Sankarathi, et al.
Publicado: (2010)

Effect of Bevacizumab on the Viability and Metabolism of Human Corneal Epithelial and Endothelial Cells: An In Vitro Study
por: Shokoohi, Shayan, et al.
Publicado: (2021)

Effects of bevacizumab on the neovascular membrane of proliferative diabetic retinopathy: reduction of endothelial cells and expressions of VEGF and HIF-1α
por: Han, Xiao-Xia, et al.
Publicado: (2012)

Evaluation of the iPad as a low vision aid for improving reading ability
por: Haji, Shamim A, et al.
Publicado: (2014)

Characterization of Vitreous and Aqueous Proteome in Humans With Proliferative Diabetic Retinopathy and Its Clinical Correlation
por: Balaiya, Sankarathi, et al.
Publicado: (2017)

An in vitro study on the effect of bevacizumab on endothelial cell proliferation and VEGF concentration level in patients with hereditary hemorrhagic telangiectasia
por: Sadick, Haneen, et al.
Publicado: (2022)

Bevacizumab Efficiently Inhibits VEGF-Associated Cellular Processes in Equine Umbilical Vein Endothelial Cells: An In Vitro Characterization
por: Lessiak, Ulrike, et al.
Publicado: (2023)

Spectral Domain OCT Documented Resolution of Pseudophakic Cystoid Macular Edema after Intravitreal Triamcinolone
por: Murthy, Ravi K, et al.
Publicado: (2010)

The Effect of Bevacizumab on Corneal Neovascularization in Rabbits
por: Kim, Wung-Jae, et al.
Publicado: (2010)

Osmolarity and spectrophotometric property of brilliant blue green define the degree of toxicity on retinal pigment epithelial cells exposed to surgical endoilluminator
por: Balaiya, Sankarathi, et al.
Publicado: (2016)

Short-term effects and safety of an acute increase of intraocular pressure after intravitreal bevacizumab injection on corneal endothelial cells
por: Park, Jiwoong, et al.
Publicado: (2018)

Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms
por: Su, Wen, et al.
Publicado: (2020)

Bilateral isolated concurrent superior ophthalmic vein thrombosis in systemic lupus erythematosus
por: Sambhav, Kumar, et al.
Publicado: (2015)

Successful Management of Complex Rhegmatogenous Retinal Detachment in Congenital Glaucoma
por: Gasparian, Suzie, et al.
Publicado: (2021)

Resolution of Refractory Corneal Neovascularization with Subconjunctival Bevacizumab
por: Britton, Anna Krystyna, et al.
Publicado: (2020)

Inverse Argyll Robertson pupil in Burkitt’s lymphoma
por: Chalam, Kakarla V, et al.
Publicado: (2008)

The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a host-blockade of VEGF clearance
por: Alidzanovic, Lejla, et al.
Publicado: (2016)

Comparison of non-viral methods to genetically modify and enrich populations of primary human corneal endothelial cells
por: Engler, Christoph, et al.
Publicado: (2009)

VEGF-A enhances the cytotoxic function of CD4(+) cytotoxic T cells via the VEGF-receptor 1/VEGF-receptor 2/AKT/mTOR pathway
por: Chen, Ziyi, et al.
Publicado: (2023)

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling
por: Stefanini, Marianne O., et al.
Publicado: (2009)

Effect of Distance and Duration of Illumination on Retinal Ganglion Cells Exposed to Varying Concentrations of Brilliant Blue Green
por: Chalam, Kakarla V., et al.
Publicado: (2015)

Safety and efficacy of human ESC-derived corneal endothelial cells for corneal endothelial dysfunction
por: Yu, Juan, et al.
Publicado: (2023)

Effect of Selenium-Enriched Garlic Oil against Cytotoxicity Induced by OX-LDL in Endothelial Cells
por: Yang, Cheng, et al.
Publicado: (2014)

Limitations in assessing nerve growth factor levels in aqueous humor samples from human eyes
por: Chalam, Kakarla V, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_d00ph6af0aaj5uggm8kn9skpfg