Cargando…
The Absence of MIST1 Leads to Increased Ethanol Sensitivity and Decreased Activity of the Unfolded Protein Response in Mouse Pancreatic Acinar Cells
BACKGROUND: Alcohol abuse is a leading cause of pancreatitis in humans. However, rodent models suggest that alcohol only sensitizes the pancreas to subsequent insult, indicating that additional factors play a role in alcohol-induced pancreatic injury. The goal of this study was to determine if an ab...
Autores principales: | Alahari, Sruthi, Mehmood, Rashid, Johnson, Charis L., Pin, Christopher L. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247225/ https://www.ncbi.nlm.nih.gov/pubmed/22216129 http://dx.doi.org/10.1371/journal.pone.0028863 |
Ejemplares similares
-
Epigenetic Reprogramming in Mist1(−/−) Mice Predicts the Molecular Response to Cerulein-Induced Pancreatitis
por: Mehmood, Rashid, et al.
Publicado: (2014) -
The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity
por: Pin, Christopher L., et al.
Publicado: (2001) -
Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model
por: Waldron, Richard T., et al.
Publicado: (2018) -
Activating transcription factor 3 promotes loss of the acinar cell phenotype in response to cerulein-induced pancreatitis in mice
por: Fazio, Elena N., et al.
Publicado: (2017) -
Acinar cell injury induced by inadequate unfolded protein response in acute pancreatitis
por: Barrera, Kaylene, et al.
Publicado: (2018)