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Nitric Oxide-Sensitive Guanylyl Cyclase Is Differentially Regulated by Nuclear and Non-Nuclear Estrogen Pathways in Anterior Pituitary Gland
17β-estradiol (E2) regulates hormonal release as well as proliferation and cell death in the pituitary. The main nitric oxide receptor, nitric oxide sensitive- or soluble guanylyl cyclase (sGC), is a heterodimer composed of two subunits, α and β, that catalyses cGMP formation. α1β1 is the most abund...
Autores principales: | Cabilla, Jimena P., Nudler, Silvana I., Ronchetti, Sonia A., Quinteros, Fernanda A., Lasaga, Mercedes, Duvilanski, Beatriz H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247256/ https://www.ncbi.nlm.nih.gov/pubmed/22216273 http://dx.doi.org/10.1371/journal.pone.0029402 |
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