Cargando…

A Genome-Wide Association Study of the Protein C Anticoagulant Pathway

The Protein C anticoagulant pathway regulates blood coagulation by preventing the inadequate formation of thrombi. It has two main plasma components: protein C and protein S. Individuals with protein C or protein S deficiency present a dramatically increased incidence of thromboembolic disorders. He...

Descripción completa

Detalles Bibliográficos
Autores principales:	Athanasiadis, Georgios, Buil, Alfonso, Souto, Juan Carlos, Borrell, Montserrat, López, Sonia, Martinez-Perez, Angel, Lathrop, Mark, Fontcuberta, Jordi, Almasy, Laura, Soria, José Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247258/ https://www.ncbi.nlm.nih.gov/pubmed/22216198 http://dx.doi.org/10.1371/journal.pone.0029168

Ejemplares similares

Sex-Specific Regulation of Mitochondrial DNA Levels: Genome-Wide Linkage Analysis to Identify Quantitative Trait Loci
por: López, Sonia, et al.
Publicado: (2012)

Searching for master regulators of transcription in a human gene expression data set
por: Buil, Alfonso, et al.
Publicado: (2007)

A new gene-based association test for genome-wide association studies
por: Buil, Alfonso, et al.
Publicado: (2009)

Integrated GWAS and Gene Expression Suggest ORM1 as a Potential Regulator of Plasma Levels of Cell-Free DNA and Thrombosis Risk
por: Lopez, Sonia, et al.
Publicado: (2022)

Smoothing of the bivariate LOD score for non-normal quantitative traits
por: Buil, Alfonso, et al.
Publicado: (2005)

The Central Role of KNG1 Gene as a Genetic Determinant of Coagulation Pathway-Related Traits: Exploring Metaphenotypes
por: Brunel, Helena, et al.
Publicado: (2016)

Identification of Antithrombin-Modulating Genes. Role of LARGE, a Gene Encoding a Bifunctional Glycosyltransferase, in the Secretion of Proteins?
por: de la Morena-Barrio, María Eugenia, et al.
Publicado: (2013)

Genetic Contribution of Femoral Neck Bone Geometry to the Risk of Developing Osteoporosis: A Family-Based Study
por: Hernandez-de Sosa, Nerea, et al.
Publicado: (2016)

Genetic Determinants of Thrombin Generation and Their Relation to Venous Thrombosis: Results from the GAIT-2 Project
por: Martin-Fernandez, Laura, et al.
Publicado: (2016)

A comparison of discrete versus continuous environment in a variance components-based linkage analysis of the COGA data
por: Viel, Kevin R, et al.
Publicado: (2005)

A comprehensive map of genetic relationships among diagnostic categories based on 48.6 million relative pairs from the Danish genealogy
por: Athanasiadis, Georgios, et al.
Publicado: (2022)

A validated clinical-genetic score for assessing the risk of thrombosis in patients with COVID-19 receiving thromboprophylaxis
por: Soria, José Manuel, et al.
Publicado: (2022)

Influence of ABO Locus on PFA-100 Collagen-ADP Closure Time Is Not Totally Dependent on the Von Willebrand Factor. Results of a GWAS on GAIT-2 Project Phenotypes
por: Pujol-Moix, Núria, et al.
Publicado: (2019)

Venous Thromboembolism While on Anticoagulation With Apixaban
por: Mazahreh, Farah, et al.
Publicado: (2021)

Immunothrombotic dysregulation in chagas disease and COVID-19: a comparative study of anticoagulation
por: Pérez-Campos Mayoral, Laura, et al.
Publicado: (2021)

Direct Oral Anticoagulants or Standard Anticoagulant Therapy in Fragile Patients with Venous Thromboembolism
por: López-Núñez, Juan J., et al.
Publicado: (2019)

Necrotizing Pancreatitis: To Anticoagulate or Not to Anticoagulate?
por: Abi-Saleh, Simon P, et al.
Publicado: (2022)

Next generation sequencing to dissect the genetic architecture of KNG1 and F11 loci using factor XI levels as an intermediate phenotype of thrombosis
por: Martin-Fernandez, Laura, et al.
Publicado: (2017)

Four variants in transferrin and HFE genes as potential markers of iron deficiency anaemia risk: an association study in menstruating women
por: Blanco-Rojo, Ruth, et al.
Publicado: (2011)

Identification of a Novel Quantitative Trait Nucleotype Related to Iron Status in a Calcium Channel Gene
por: Baeza-Richer, Carlos, et al.
Publicado: (2013)

Cost-effectiveness analysis of dabigatran and anticoagulation monitoring strategies of vitamin K antagonist
por: Carles, Misericòrdia, et al.
Publicado: (2015)

Pharmacogenetic studies with oral anticoagulants. Genome-wide association studies in vitamin K antagonist and direct oral anticoagulants
por: Cullell, Natalia, et al.
Publicado: (2018)

Genome-wide discovery of maternal effect variants
por: Kent, Jack W, et al.
Publicado: (2009)

Key pathways and genes that are altered during treatment with hyperbaric oxygen in patients with sepsis due to necrotizing soft tissue infection (HBOmic study)
por: Vinkel, Julie, et al.
Publicado: (2023)

Wide-Band Color Imagery Restoration for RGB-NIR Single Sensor Images
por: Soria, Xavier, et al.
Publicado: (2018)

Effect of Previous Anticoagulant Treatment on Risk of COVID-19
por: Zapata-Cachafeiro, Maruxa, et al.
Publicado: (2022)

Consensus Statement on Hemostatic Management, Anticoagulation, and Antiplatelet Therapy in Liver Transplantation
por: Montalvá, Eva, et al.
Publicado: (2022)

Data for GAW20: genome-wide DNA sequence variation and epigenome-wide DNA methylation before and after fenofibrate treatment in a family study of metabolic phenotypes
por: Aslibekyan, Stella, et al.
Publicado: (2018)

Dataset on the concentrations of anticoagulant rodenticides in raptors from the Canary Islands with geographic information
por: Rial-Berriel, Cristian, et al.
Publicado: (2021)

Clinical pharmacist led hospital-wide direct oral anticoagulant stewardship program
por: Perlman, Amichai, et al.
Publicado: (2019)

A variance component method for integrated pathway analysis of gene expression data
por: Quillen, Ellen E., et al.
Publicado: (2016)

Anticoagulation for Left Ventricle Thrombus—Case Series and Literature Review for Use of Direct Oral Anticoagulants
por: Pradhan, Akshyaya, et al.
Publicado: (2023)

P1664: WHICH FACTORS DO IMPACT IN OPTIMAL ANTICOAGULATION IN ANTIPHOSPHOLIPID SYNDROME?
por: Ontiveros-Austria, Juan Luis, et al.
Publicado: (2023)

Clinical outcomes in patients with atrial fibrillation treated with DOACs in a specialized anticoagulation center: Critical appraisal of real-world data
por: Moret, Carla, et al.
Publicado: (2023)

Effects on linkage analyses of different Affymetrix expression measures as quantitative trait phenotypes
por: Peralta, Juan Manuel, et al.
Publicado: (2007)

Dextran and hydroxyethyl starch do not interfere with fibrinogen measurement if Clauss method with mechanical clot detection is used
por: Mateo, Jose, et al.
Publicado: (2011)

Bayés’ syndrome: Time to consider early anticoagulation?
por: Baranchuk, Adrian, et al.
Publicado: (2018)

Genome wide expression analysis in HPV16 Cervical Cancer: identification of altered metabolic pathways
por: Pérez-Plasencia, Carlos, et al.
Publicado: (2007)

Effects of covariates and interactions on a genome-wide association analysis of rheumatoid arthritis
por: Arya, Rector, et al.
Publicado: (2009)

A survey of genetic simulation software for population and epidemiological studies
por: Liu, Youfang, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_4aaan1a6ej4d3ohl5gmkqgimte