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A Viral Vectored Prime-Boost Immunization Regime Targeting the Malaria Pfs25 Antigen Induces Transmission-Blocking Activity
The ookinete surface protein Pfs25 is a macrogamete-to-ookinete/ookinete stage antigen of Plasmodium falciparum, capable of exerting high-level anti-malarial transmission-blocking activity following immunization with recombinant protein-in-adjuvant formulations. Here, this antigen was expressed in r...
Autores principales: | Goodman, Anna L., Blagborough, Andrew M., Biswas, Sumi, Wu, Yimin, Hill, Adrian V., Sinden, Robert E., Draper, Simon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247263/ https://www.ncbi.nlm.nih.gov/pubmed/22216279 http://dx.doi.org/10.1371/journal.pone.0029428 |
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