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rac-syn-Diethyl 2-hy­droxy-4-oxo-1-phenyl­cyclo­hexane-1,2-dicarboxyl­ate

The title compound, C(18)H(22)O(6), was obtained by the domino oxa–Michael–aldol (DOMA) reaction and has the cyclo­hexa­none ring in a chair conformation with intra-annular torsion angles in the range 49.9 (2)–58.9 (2)°. The two eth­oxy­carbonyl substituents on the cyclo­hexa­none ring adopt a syn c...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Jun, Ni, Sheng-Liang, Meng, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247381/
https://www.ncbi.nlm.nih.gov/pubmed/22219999
http://dx.doi.org/10.1107/S1600536811042048
Descripción
Sumario:The title compound, C(18)H(22)O(6), was obtained by the domino oxa–Michael–aldol (DOMA) reaction and has the cyclo­hexa­none ring in a chair conformation with intra-annular torsion angles in the range 49.9 (2)–58.9 (2)°. The two eth­oxy­carbonyl substituents on the cyclo­hexa­none ring adopt a syn configurations. In the crystal, the mol­ecules self-assemble through duplex inter­molecular hy­droxy–carbonyl O—H⋯O hydrogen bonds, giving centrosymmetric cyclic dimers [graph set R (2) (2)(12)] which inter-associate through weak C—H⋯O hydrogen-bonding inter­actions.