Cargando…
rac-syn-Diethyl 2-hydroxy-4-oxo-1-phenylcyclohexane-1,2-dicarboxylate
The title compound, C(18)H(22)O(6), was obtained by the domino oxa–Michael–aldol (DOMA) reaction and has the cyclohexanone ring in a chair conformation with intra-annular torsion angles in the range 49.9 (2)–58.9 (2)°. The two ethoxycarbonyl substituents on the cyclohexanone ring adopt a syn c...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247381/ https://www.ncbi.nlm.nih.gov/pubmed/22219999 http://dx.doi.org/10.1107/S1600536811042048 |
Sumario: | The title compound, C(18)H(22)O(6), was obtained by the domino oxa–Michael–aldol (DOMA) reaction and has the cyclohexanone ring in a chair conformation with intra-annular torsion angles in the range 49.9 (2)–58.9 (2)°. The two ethoxycarbonyl substituents on the cyclohexanone ring adopt a syn configurations. In the crystal, the molecules self-assemble through duplex intermolecular hydroxy–carbonyl O—H⋯O hydrogen bonds, giving centrosymmetric cyclic dimers [graph set R (2) (2)(12)] which inter-associate through weak C—H⋯O hydrogen-bonding interactions. |
---|