Tris(dicyclo­hexyl­ammonium) hydrogen [1-hy­droxy-2-(1H-imidazol-1-yl)-1-phospho­natoethane]­phospho­nate ethanol monosolvate mono­hydrate

In the title compound, 3C(12)H(24)N(+)·C(5)H(7)N(2)O(7)P(2) (3−)·C(2)H(6)O·H(2)O, the zoledronic acid mol­ecule is singly protonated and stabilized by an intra­molecular O—H⋯O inter­action. The three-dimensional crystal structure is stabilized by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O inter­actions....

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Detalles Bibliográficos
Autores principales: Sarkar, Anindita, Cukrowski, Ignacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247383/
https://www.ncbi.nlm.nih.gov/pubmed/22220001
http://dx.doi.org/10.1107/S1600536811042206
Descripción
Sumario:In the title compound, 3C(12)H(24)N(+)·C(5)H(7)N(2)O(7)P(2) (3−)·C(2)H(6)O·H(2)O, the zoledronic acid mol­ecule is singly protonated and stabilized by an intra­molecular O—H⋯O inter­action. The three-dimensional crystal structure is stabilized by inter­molecular O—H⋯O, O—H⋯N and N—H⋯O inter­actions. The ethanol solvent mol­ecule is disordered over two positions; the site-occupancy factor of the major component is 0.510 (4).

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