Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate

In the mol­ecule of the title compound, C(18)H(22)N(2)O(3), the dihydro­pyrimidinone ring adopts an envelope conformation. The dihedral angle between the phenyl ring and the mean plane through the enamine fragment is 86.04 (7)°. The mol­ecular conformation is stabilized by an intra­molecular C—H⋯O h...

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Autores principales: Wang, Xi-Cun, Tang, Xue-Hong, Da, Yu-Xia, Zhang, Zhang, Quan, Zheng-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247395/
https://www.ncbi.nlm.nih.gov/pubmed/22220013
http://dx.doi.org/10.1107/S1600536811042243
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author Wang, Xi-Cun
Tang, Xue-Hong
Da, Yu-Xia
Zhang, Zhang
Quan, Zheng-Jun
author_facet Wang, Xi-Cun
Tang, Xue-Hong
Da, Yu-Xia
Zhang, Zhang
Quan, Zheng-Jun
author_sort Wang, Xi-Cun
collection PubMed
description In the mol­ecule of the title compound, C(18)H(22)N(2)O(3), the dihydro­pyrimidinone ring adopts an envelope conformation. The dihedral angle between the phenyl ring and the mean plane through the enamine fragment is 86.04 (7)°. The mol­ecular conformation is stabilized by an intra­molecular C—H⋯O hydrogen bond. In the crystal, inter­molecular N—H⋯O hydrogen bonds link pairs of mol­ecules into centrosymmetric dimers.
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spelling pubmed-32473952012-01-04 Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate Wang, Xi-Cun Tang, Xue-Hong Da, Yu-Xia Zhang, Zhang Quan, Zheng-Jun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the mol­ecule of the title compound, C(18)H(22)N(2)O(3), the dihydro­pyrimidinone ring adopts an envelope conformation. The dihedral angle between the phenyl ring and the mean plane through the enamine fragment is 86.04 (7)°. The mol­ecular conformation is stabilized by an intra­molecular C—H⋯O hydrogen bond. In the crystal, inter­molecular N—H⋯O hydrogen bonds link pairs of mol­ecules into centrosymmetric dimers. International Union of Crystallography 2011-10-22 /pmc/articles/PMC3247395/ /pubmed/22220013 http://dx.doi.org/10.1107/S1600536811042243 Text en © Wang et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Wang, Xi-Cun
Tang, Xue-Hong
Da, Yu-Xia
Zhang, Zhang
Quan, Zheng-Jun
Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_full Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_fullStr Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_full_unstemmed Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_short Ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
title_sort ethyl 6-methyl-3-(2-methyl­prop-1-en­yl)-2-oxo-4-phenyl-1,2,3,4-tetra­hydro­pyrimidine-5-carboxyl­ate
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247395/
https://www.ncbi.nlm.nih.gov/pubmed/22220013
http://dx.doi.org/10.1107/S1600536811042243
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