(6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone

In the title compound {systematic name: N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-aza­tricyclo­[6.3.0.0(2,5)]undec-1(8)-en-4-yl]-2-phenyl­acetamide}, C(16)H(14)N(2)O(4)S, the four- and five-membered rings adopt planar conformations (with r.m.s. deviations of 0.0349 and 0.0108 Å respectively) while the s...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao-Liang, Wang, Hao, Wang, Yan, Shi, Pei-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247487/
https://www.ncbi.nlm.nih.gov/pubmed/22220105
http://dx.doi.org/10.1107/S1600536811043881
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author Zhou, Xiao-Liang
Wang, Hao
Wang, Yan
Shi, Pei-Ji
author_facet Zhou, Xiao-Liang
Wang, Hao
Wang, Yan
Shi, Pei-Ji
author_sort Zhou, Xiao-Liang
collection PubMed
description In the title compound {systematic name: N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-aza­tricyclo­[6.3.0.0(2,5)]undec-1(8)-en-4-yl]-2-phenyl­acetamide}, C(16)H(14)N(2)O(4)S, the four- and five-membered rings adopt planar conformations (with r.m.s. deviations of 0.0349 and 0.0108 Å respectively) while the six-membered ring adopts a half-chair, or envelope-like, conformation with the S atom in the flap position. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds.
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spelling pubmed-32474872012-01-04 (6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone Zhou, Xiao-Liang Wang, Hao Wang, Yan Shi, Pei-Ji Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound {systematic name: N-[(4R,5R)-3,11-dioxo-10-oxa-6-thia-2-aza­tricyclo­[6.3.0.0(2,5)]undec-1(8)-en-4-yl]-2-phenyl­acetamide}, C(16)H(14)N(2)O(4)S, the four- and five-membered rings adopt planar conformations (with r.m.s. deviations of 0.0349 and 0.0108 Å respectively) while the six-membered ring adopts a half-chair, or envelope-like, conformation with the S atom in the flap position. In the crystal, mol­ecules are linked by N—H⋯O hydrogen bonds. International Union of Crystallography 2011-10-29 /pmc/articles/PMC3247487/ /pubmed/22220105 http://dx.doi.org/10.1107/S1600536811043881 Text en © Zhou et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Zhou, Xiao-Liang
Wang, Hao
Wang, Yan
Shi, Pei-Ji
(6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
title (6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
title_full (6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
title_fullStr (6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
title_full_unstemmed (6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
title_short (6R,7R)-3-Hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
title_sort (6r,7r)-3-hydroxymethyl-7-(2-phenyl­acetamido)-3-cephem-4-carboxylic acid lactone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247487/
https://www.ncbi.nlm.nih.gov/pubmed/22220105
http://dx.doi.org/10.1107/S1600536811043881
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