4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline

In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra­molecular C—H⋯O hydrogen bo...

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Detalles Bibliográficos
Autores principales: Fun, Hoong-Kun, Arshad, Suhana, Garudachari, B., Isloor, Arun M., Satyanarayan, M. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247502/
https://www.ncbi.nlm.nih.gov/pubmed/22220120
http://dx.doi.org/10.1107/S1600536811044370
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author Fun, Hoong-Kun
Arshad, Suhana
Garudachari, B.
Isloor, Arun M.
Satyanarayan, M. N.
author_facet Fun, Hoong-Kun
Arshad, Suhana
Garudachari, B.
Isloor, Arun M.
Satyanarayan, M. N.
author_sort Fun, Hoong-Kun
collection PubMed
description In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra­molecular C—H⋯O hydrogen bond generates an S(7) ring motif. In the crystal, mol­ecules are linked into infinite chains along the b axis by C—H⋯N hydrogen bonds.
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spelling pubmed-32475022012-01-04 4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline Fun, Hoong-Kun Arshad, Suhana Garudachari, B. Isloor, Arun M. Satyanarayan, M. N. Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(23)H(20)F(3)N(5)O, the piperazine ring adopts a chair conformation. The quinoline ring makes dihedral angles of 56.61 (11), 49.94 (12) and 42.58 (14)° with the piperazine ring, the 1,3,4-oxadiazole ring and the benzene ring, respectively. An intra­molecular C—H⋯O hydrogen bond generates an S(7) ring motif. In the crystal, mol­ecules are linked into infinite chains along the b axis by C—H⋯N hydrogen bonds. International Union of Crystallography 2011-10-29 /pmc/articles/PMC3247502/ /pubmed/22220120 http://dx.doi.org/10.1107/S1600536811044370 Text en © Fun et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Fun, Hoong-Kun
Arshad, Suhana
Garudachari, B.
Isloor, Arun M.
Satyanarayan, M. N.
4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
title 4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
title_full 4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
title_fullStr 4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
title_full_unstemmed 4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
title_short 4-(4-Methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
title_sort 4-(4-methyl­piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro­meth­yl)quinoline
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247502/
https://www.ncbi.nlm.nih.gov/pubmed/22220120
http://dx.doi.org/10.1107/S1600536811044370
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