(4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)

The crystal structure of the title compound, C(16)H(28)O, features C—H⋯O hydrogen bonds making C(6) zigzag chains along one 2(1) screw axis. Within the limits of the data collection affected by crystal quality, the Hooft parameter gave correct indications of the known molecular chirality based on th...

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Detalles Bibliográficos
Autores principales: Evans, Gary B., Gainsford, Graeme J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247605/
https://www.ncbi.nlm.nih.gov/pubmed/22219910
http://dx.doi.org/10.1107/S1600536811038694
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author Evans, Gary B.
Gainsford, Graeme J.
author_facet Evans, Gary B.
Gainsford, Graeme J.
author_sort Evans, Gary B.
collection PubMed
description The crystal structure of the title compound, C(16)H(28)O, features C—H⋯O hydrogen bonds making C(6) zigzag chains along one 2(1) screw axis. Within the limits of the data collection affected by crystal quality, the Hooft parameter gave correct indications of the known molecular chirality based on the single O atom anomalous dispersion in contrast to the indeterminate Flack value. Synthetic steps starting from manool are reported.
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spelling pubmed-32476052012-01-04 (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber) Evans, Gary B. Gainsford, Graeme J. Acta Crystallogr Sect E Struct Rep Online Organic Papers The crystal structure of the title compound, C(16)H(28)O, features C—H⋯O hydrogen bonds making C(6) zigzag chains along one 2(1) screw axis. Within the limits of the data collection affected by crystal quality, the Hooft parameter gave correct indications of the known molecular chirality based on the single O atom anomalous dispersion in contrast to the indeterminate Flack value. Synthetic steps starting from manool are reported. International Union of Crystallography 2011-10-08 /pmc/articles/PMC3247605/ /pubmed/22219910 http://dx.doi.org/10.1107/S1600536811038694 Text en © Evans and Gainsford 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Evans, Gary B.
Gainsford, Graeme J.
(4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)
title (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)
title_full (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)
title_fullStr (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)
title_full_unstemmed (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)
title_short (4aR,6aS,10aR,10bS)-7,7,10a-Trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2H-naphtho­[2,1-c]pyran (Pyamber)
title_sort (4ar,6as,10ar,10bs)-7,7,10a-trimethyl-1,4,4a,5,6,6a,7,8,9,10,10a,10b-dodecahydro-2h-naphtho­[2,1-c]pyran (pyamber)
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247605/
https://www.ncbi.nlm.nih.gov/pubmed/22219910
http://dx.doi.org/10.1107/S1600536811038694
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