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(S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide
The title compound, C(24)H(23)N(3)O(3)S(2), crystallizes with two independent molecules in the asymmetric unit. They differ essentially in the orientation of the tolyl rings, between which there is π–π stacking (centroid–centroid distance = 3.01 Å). The absolute configuration was confirmed by the d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247610/ https://www.ncbi.nlm.nih.gov/pubmed/22219915 http://dx.doi.org/10.1107/S1600536811040669 |
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author | Syed, Tayyaba Hameed, Shahid Jones, Peter G. |
author_facet | Syed, Tayyaba Hameed, Shahid Jones, Peter G. |
author_sort | Syed, Tayyaba |
collection | PubMed |
description | The title compound, C(24)H(23)N(3)O(3)S(2), crystallizes with two independent molecules in the asymmetric unit. They differ essentially in the orientation of the tolyl rings, between which there is π–π stacking (centroid–centroid distance = 3.01 Å). The absolute configuration was confirmed by the determination of the Flack parameter [x = 0.008 (9)]. In the crystal, molecules are connected by two classical N—H⋯N hydrogen bonds and two weak but very short C—H⋯O(sulfonyl) interactions, forming layers lying parallel to the bc plane. |
format | Online Article Text |
id | pubmed-3247610 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-32476102012-01-04 (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide Syed, Tayyaba Hameed, Shahid Jones, Peter G. Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(24)H(23)N(3)O(3)S(2), crystallizes with two independent molecules in the asymmetric unit. They differ essentially in the orientation of the tolyl rings, between which there is π–π stacking (centroid–centroid distance = 3.01 Å). The absolute configuration was confirmed by the determination of the Flack parameter [x = 0.008 (9)]. In the crystal, molecules are connected by two classical N—H⋯N hydrogen bonds and two weak but very short C—H⋯O(sulfonyl) interactions, forming layers lying parallel to the bc plane. International Union of Crystallography 2011-10-08 /pmc/articles/PMC3247610/ /pubmed/22219915 http://dx.doi.org/10.1107/S1600536811040669 Text en © Syed et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers Syed, Tayyaba Hameed, Shahid Jones, Peter G. (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
title | (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
title_full | (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
title_fullStr | (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
title_full_unstemmed | (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
title_short | (S)-N-[1-(5-Benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
title_sort | (s)-n-[1-(5-benzylsulfanyl-1,3,4-oxadiazol-2-yl)-2-phenylethyl]-4-methylbenzenesulfonamide |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247610/ https://www.ncbi.nlm.nih.gov/pubmed/22219915 http://dx.doi.org/10.1107/S1600536811040669 |
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