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PKA regulatory subunits mediate synergy among conserved G-protein-coupled receptor cascades

G-protein-coupled receptors sense extracellular chemical or physical stimuli and transmit these signals to distinct trimeric G-proteins. Activated Gα-proteins route signals to interconnected effector cascades, thus regulating thresholds, amplitudes and durations of signalling. Gαs- or Gαi-coupled re...

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Detalles Bibliográficos
Autores principales:	Stefan, Eduard, Malleshaiah, Mohan K., Breton, Billy, Ear, Po Hien, Bachmann, Verena, Beyermann, Michael, Bouvier, Michel, Michnick, Stephen W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247815/ https://www.ncbi.nlm.nih.gov/pubmed/22186894 http://dx.doi.org/10.1038/ncomms1605

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