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Estimates of array and pool-construction variance for planning efficient DNA-pooling genome wide association studies
BACKGROUND: Until recently, genome-wide association studies (GWAS) have been restricted to research groups with the budget necessary to genotype hundreds, if not thousands, of samples. Replacing individual genotyping with genotyping of DNA pools in Phase I of a GWAS has proven successful, and dramat...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247851/ https://www.ncbi.nlm.nih.gov/pubmed/22122996 http://dx.doi.org/10.1186/1755-8794-4-81 |