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Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line

BACKGROUND: Cowden Syndrome (CS) patients with germ line point mutations in the PTEN gene are at high risk for developing breast cancer. It is believed that cells harboring these mutant PTEN alleles are predisposed to malignant conversion. This article will characterize the biochemical and biologica...

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Detalles Bibliográficos
Autores principales:	Singh, Gobind, Odriozola, Leticia, Guan, Hong, Kennedy, Colin R, Chan, Andrew M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247870/ https://www.ncbi.nlm.nih.gov/pubmed/22103913 http://dx.doi.org/10.1186/1471-2407-11-490

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