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Improved spinal fusion efficacy by long-term delivery of bone morphogenetic protein-2 in a rabbit model

BACKGROUND AND PURPOSE: Various new delivery systems for recombinant human bone morphogenetic protein-2 (rhBMP-2) have been introduced to improve its efficacy in osteogenesis. Of these, we have previously developed heparin-conjugated PLGA nanospheres (HCPN) as a long-term delivery system for BMP-2....

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Detalles Bibliográficos
Autores principales:	Lee, Jae-Wook, Lee, Saehyoung, Lee, Sun Hwa, Yang, Hee Seok, Im, Gun-II, Kim, Chang-Sung, Park, Jung-Ho, Kim, Byung Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Informa Healthcare 2011
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3247898/ https://www.ncbi.nlm.nih.gov/pubmed/22066556 http://dx.doi.org/10.3109/17453674.2011.636675

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