Addiction of MYCN Amplified Tumours to B-MYB Underscores a Reciprocal Regulatory Loop

MYCN is a member of the MYC family of oncoproteins frequently amplified or overexpressed in aggressive, paediatric tumours of the nervous system. In this study we have identified the gene B-MYB, encoding the transcription factor also known as MYBL2, as a downstream target of MYCN. Using multiple in...

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Detalles Bibliográficos
Autores principales: Gualdrini, Francesco, Corvetta, Daisy, Cantilena, Sandra, Chayka, Olesya, Tanno, Barbara, Raschellà, Giuseppe, Sala, Arturo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248110/
https://www.ncbi.nlm.nih.gov/pubmed/21304178

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