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Drug Discovery Approaches to Target Wnt Signaling in Cancer Stem Cells
Cancer stem cells (CSCs) represent a unique subset of cells within a tumor that possess self-renewal capacity and pluripotency, and can drive tumor initiation and maintenance. First identified in hematological malignancies, CSCs are now thought to play an important role in a wide variety of solid tu...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248130/ https://www.ncbi.nlm.nih.gov/pubmed/21317452 http://dx.doi.org/10.18632/oncotarget.191 |