The requirement of p53 for maintaining chromosomal stability during tetraploidization

Tetraploidization is believed to promote genome instability and tumorigenesis. Whether tetraploids per se are intrinsically unstable and transforming remain incompletely understood. In this report, tetraploidization was induced with cell fusion using mouse fibroblasts. Due to the unequal segregation...

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Detalles Bibliográficos
Autores principales: Ho, Chui Chui, Hau, Pok Man, Marxer, Miriam, Poon, Randy Y.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248137/
https://www.ncbi.nlm.nih.gov/pubmed/21317454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248137/
https://www.ncbi.nlm.nih.gov/pubmed/21317454

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