Targeting tumor angiogenesis with TSP-1-based compounds: rational design of antiangiogenic mimetics of endogenous inhibitors

Inhibitors of angiogenesis are an important addition to conventional chemotherapy. Among different “druggable” angiogenic factors, fibroblast growth factor-2 (FGF-2) is an attractive target for novel therapies because of its intricated involvement in tumor neovascularization, tumor cell proliferatio...

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Detalles Bibliográficos
Autores principales: Taraboletti, Giulia, Rusnati, Marco, Ragona, Laura, Colombo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Perspectives
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248139/
https://www.ncbi.nlm.nih.gov/pubmed/21317461

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