Expression of FACT in mammalian tissues suggests its role in maintaining of undifferentiated state of cells

The Facilitates Chromatin Transcription (FACT) chromatin remodeling complex, comprised of two subunits, SSRP1 and SPT16, is involved in transcription, replication and DNA repair. We recently showed that curaxins, small molecules with anti-cancer activity, target FACT and kill tumor cells in a FACT-d...

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Detalles Bibliográficos
Autores principales: Garcia, Henry, Fleyshman, Daria, Kolesnikova, Katerina, Safina, Alfiya, Commane, Mairead, Paszkiewicz, Geraldine, Omelian, Angela, Morrison, Carl, Gurova, Kateryna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248156/
https://www.ncbi.nlm.nih.gov/pubmed/21998152

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