Cargando…
p21-activated kinase 1: PAK'ed with potential
The p21-activated kinases (PAKs) are central players in growth factor signaling networks and morphogenetic processes that control proliferation, cell polarity, invasion and actin cytoskeleton organization. This raises the possibility that interfering with PAK activity may produce significant anti-tu...
Autores principales: | Ong, Christy C., Jubb, Adrian M., Zhou, Wei, Haverty, Peter M., Harris, Adrian L., Belvin, Marcia, Friedman, Lori S., Koeppen, Hartmut, Hoeflich, Klaus P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248206/ https://www.ncbi.nlm.nih.gov/pubmed/21653999 |
Ejemplares similares
-
Small molecule inhibition of group I p21-activated kinases in breast cancer induces apoptosis and potentiates the activity of microtubule stabilizing agents
por: Ong, Christy C, et al.
Publicado: (2015) -
A practical implementation of de-Pake-ing via weighted Fourier transformation
por: Sani, Marc-Antoine, et al.
Publicado: (2013) -
Group I Paks as therapeutic targets in NF2-deficient meningioma
por: Chow, Hoi-Yee, et al.
Publicado: (2015) -
Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs
por: Eswaran, Jeyanthy, et al.
Publicado: (2007) -
The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
por: Møller, Lisbeth L. V., et al.
Publicado: (2020)