Assessment of EGFR/HER2 dimerization by FRET-FLIM utilizing Alexa-conjugated secondary antibodies in relation to targeted therapies in cancers

The expression level of the HER family is unreliable as a predictive marker for targeted therapies in cancer. Thus, there is a need to develop other biomarkers, which can be used to accurately select responsive patients for targeted therapies. The HER dimerization status may be more important than H...

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Detalles Bibliográficos
Autores principales: Waterhouse, Benjamin R., Gijsen, Merel, Barber, Paul R., Tullis, Iain D.C., Vojnovic, Borivoj, Kong, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2011
Materias:
Methodological Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248220/
https://www.ncbi.nlm.nih.gov/pubmed/21908901

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