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Incidence of Acute Myeloid Leukemia after Breast Cancer

Breast cancer is the most frequent cancer among women and the leading cause of death among middle-aged women. Early detection by mammography screening and improvement of therapeutic options have increased breast cancer survival rates, with the consequence that late side effects of cancer treatment b...

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Autores principales: Valentini, Caterina Giovanna, Fianchi, Luana, Voso, Maria Teresa, Caira, Morena, Leone, Giuseppe, Pagano, Livio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Università Cattolica del Sacro Cuore 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248346/
https://www.ncbi.nlm.nih.gov/pubmed/22220266
http://dx.doi.org/10.4084/MJHID.2011.069
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author Valentini, Caterina Giovanna
Fianchi, Luana
Voso, Maria Teresa
Caira, Morena
Leone, Giuseppe
Pagano, Livio
author_facet Valentini, Caterina Giovanna
Fianchi, Luana
Voso, Maria Teresa
Caira, Morena
Leone, Giuseppe
Pagano, Livio
author_sort Valentini, Caterina Giovanna
collection PubMed
description Breast cancer is the most frequent cancer among women and the leading cause of death among middle-aged women. Early detection by mammography screening and improvement of therapeutic options have increased breast cancer survival rates, with the consequence that late side effects of cancer treatment become increasingly important. In particular, patients treated with adjuvant chemotherapy regimens, commonly including alkylating agents and anthracyclines, are at increased risk of developing leukemia, further enhanced by the use of radiotherapy. In the last few years also the use of growth factors seems to increase the risk of secondary leukemia. The purpose of this review is to update epidemiology of therapy-related myeloid neoplasms occurring in breast cancer patients.
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spelling pubmed-32483462012-01-04 Incidence of Acute Myeloid Leukemia after Breast Cancer Valentini, Caterina Giovanna Fianchi, Luana Voso, Maria Teresa Caira, Morena Leone, Giuseppe Pagano, Livio Mediterr J Hematol Infect Dis Review Articles Breast cancer is the most frequent cancer among women and the leading cause of death among middle-aged women. Early detection by mammography screening and improvement of therapeutic options have increased breast cancer survival rates, with the consequence that late side effects of cancer treatment become increasingly important. In particular, patients treated with adjuvant chemotherapy regimens, commonly including alkylating agents and anthracyclines, are at increased risk of developing leukemia, further enhanced by the use of radiotherapy. In the last few years also the use of growth factors seems to increase the risk of secondary leukemia. The purpose of this review is to update epidemiology of therapy-related myeloid neoplasms occurring in breast cancer patients. Università Cattolica del Sacro Cuore 2011-12-22 /pmc/articles/PMC3248346/ /pubmed/22220266 http://dx.doi.org/10.4084/MJHID.2011.069 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Valentini, Caterina Giovanna
Fianchi, Luana
Voso, Maria Teresa
Caira, Morena
Leone, Giuseppe
Pagano, Livio
Incidence of Acute Myeloid Leukemia after Breast Cancer
title Incidence of Acute Myeloid Leukemia after Breast Cancer
title_full Incidence of Acute Myeloid Leukemia after Breast Cancer
title_fullStr Incidence of Acute Myeloid Leukemia after Breast Cancer
title_full_unstemmed Incidence of Acute Myeloid Leukemia after Breast Cancer
title_short Incidence of Acute Myeloid Leukemia after Breast Cancer
title_sort incidence of acute myeloid leukemia after breast cancer
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248346/
https://www.ncbi.nlm.nih.gov/pubmed/22220266
http://dx.doi.org/10.4084/MJHID.2011.069
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