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Advantages of a Mechanistic Codon Substitution Model for Evolutionary Analysis of Protein-Coding Sequences
BACKGROUND: A mechanistic codon substitution model, in which each codon substitution rate is proportional to the product of a codon mutation rate and the average fixation probability depending on the type of amino acid replacement, has advantages over nucleotide, amino acid, and empirical codon subs...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248416/ https://www.ncbi.nlm.nih.gov/pubmed/22220197 http://dx.doi.org/10.1371/journal.pone.0028892 |