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Knockout of 5-Lipoxygenase Results in Age-Dependent Anxiety-Like Behavior in Female Mice
BACKGROUND: The enzyme 5-lipoxygenase (5LO) has been implicated in a variety of neurological and psychiatric disorders including anxiety. Knockout of 5LO has previously been shown to alter anxiety-like behavior in mice at a young age but the effect of 5LO knockout on older animals has not been chara...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248425/ https://www.ncbi.nlm.nih.gov/pubmed/22220211 http://dx.doi.org/10.1371/journal.pone.0029448 |