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Recovering Protein-Protein and Domain-Domain Interactions from Aggregation of IP-MS Proteomics of Coregulator Complexes
Coregulator proteins (CoRegs) are part of multi-protein complexes that transiently assemble with transcription factors and chromatin modifiers to regulate gene expression. In this study we analyzed data from 3,290 immuno-precipitations (IP) followed by mass spectrometry (MS) applied to human cell li...
Autores principales: | Mazloom, Amin R., Dannenfelser, Ruth, Clark, Neil R., Grigoryan, Arsen V., Linder, Kathryn M., Cardozo, Timothy J., Bond, Julia C., Boran, Aislyn D. W., Iyengar, Ravi, Malovannaya, Anna, Lanz, Rainer B., Ma'ayan, Avi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248428/ https://www.ncbi.nlm.nih.gov/pubmed/22219718 http://dx.doi.org/10.1371/journal.pcbi.1002319 |
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