Transcription Is Required to Establish Maternal Imprinting at the Prader-Willi Syndrome and Angelman Syndrome Locus

The Prader-Willi syndrome (PWS [MIM 17620]) and Angelman syndrome (AS [MIM 105830]) locus is controlled by a bipartite imprinting center (IC) consisting of the PWS-IC and the AS-IC. The most widely accepted model of IC function proposes that the PWS-IC activates gene expression from the paternal all...

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Detalles Bibliográficos
Autores principales: Smith, Emily Y., Futtner, Christopher R., Chamberlain, Stormy J., Johnstone, Karen A., Resnick, James L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248558/
https://www.ncbi.nlm.nih.gov/pubmed/22242001
http://dx.doi.org/10.1371/journal.pgen.1002422

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